First of all the reason to analize what is the difference betwen Powerpoint vs Keynote is that a few days I converted all the slides in the Zacomic store from PowerPoint to Keynote. That was quite a bit of conversion and uploading work… As a result I got an even better understanding of the differences between PowerPoint vs Keynote. Here is the 2018 version of the comparison.
Overall both programs are excellent, as you would expect from software that has been around this long. Bugs have been ironed out, and both programs have “learned” from each other to get to a good workflow. So the differences are not that major.
Where Powerpoint is stronger
Where Keynote is stronger
There are some charts wich Powerpoint can make and Keynote not, i found out the hard way with my conversion effort:
Both of these are not crucial to presentation design. In fact, too much 3D fire power in the hand of the layman designer might not beneficial to the quality of the slides.